is a patient support organisation to help keratoderma patients and their families


Welcome to We offer support, advice and information to keratoderma patients.

Do you or a family member have keratoderma? If so, then please register with We are building a worldwide database of patients to enable future trials of new medicines.

Keratoderma Notebooks

How can we help you? Information about various types of keratoderma can be found here, as well as details of how to obtain genetic testing for inherited forms of keratoderma.


Want to meet others with keratoderma, as well as expert doctors and scientists working on these conditions? Details of forthcoming patient support meetings can be found here.


Can you help us to help you? We are a not-for-profit patient support organisation. Our activities depend on funds raised by the public. Ways to donate can be found here.

ABOUT US is a patient advocacy organisation for patients with palmoplantar keratoderma
providing help and info to patients

What is palmoplantar keratoderma? ‘Keratoderma’ is a term that means marked thickening of the skin.

‘Palmoplantar’ refers to the skin on the soles of the feet and palms of the hands; these are the areas keratoderma affects most often. The terms "keratoderma" and "palmoplantar keratoderma" are used interchangably. Palmoplantar keratoderma is also sometimes known as ‘keratosis palmaris et plantaris’.

Classification of keratodermas depends on whether or not it is inherited, and its clinical features.

• Diffuse keratodermas affect most of the palms and soles.

• Focal keratodermas mainly affect pressure areas.

• Punctate-type keratodermas result in tiny bumps on the palms and soles.

Most often the abnormal skin involves only the palms and soles (non-transgradient) but sometimes it extends on to the top of the hands and feet as well (transgradient).

In a few rare forms of keratoderma other organs in the body may be affected in addition to the skin and in these cases, the keratoderma can be a marker of this more general abnormality.

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